Preview of the upcoming Week 3 Divisional Matchup between the Colts and the Titans.

The Colts have won four consecutive games against the Titans.

This Sunday game between the Indianapolis Colts and Tennessee Titans is crucial for the Colts. It’s their first meeting against a division opponent and their first road game of the season. The Colts, currently 2-0, are set to play at Nissan Stadium against the Titans, who are 0-2. The game will be broadcast on CBS. In Week 2, the Colts secured a win at home against the Denver Broncos, whereas the Titans suffered a defeat at home to the Los Angeles Rams. The Colts are favored by 3.5 points.

Week 2 Recap:

The Colts improved to 2-0 on the season with a heart-stopping 29-28 victory over the Denver Broncos at Lucas Oil Stadium. In a game that featured explosive offenses, controversial penalties, and a dramatic fourth-quarter comeback, the Colts overcame a late 28-20 deficit to secure their second straight win. This matchup highlighted the promise of QB Daniel Jones while exposing some defensive vulnerabilities, but ultimately, it was kicker Spencer Shrader's game-winning field goal as time expired that sent Colts Nation into euphoria.

The Titans fell to 0-2 on the season after a frustrating 33-19 home loss to the Los Angeles Rams at Nissan Stadium. In a game that started competitively but turned into a defensive showcase for L.A. in the second half. The Titans' rookie quarterback Cam Ward showed flashes of brilliance in his NFL debut but couldn't overcome a turnover and a relentless Rams pass rush, who sacked him five times. The defeat extends Tennessee's skid to eight games dating back to last season, raising early questions about the rebuild under head coach Brian Callahan. Despite some offensive sparks, penalties and self-inflicted wounds like 10 flags for 62 yards continued to plague the team, mirroring their penalty-marred Week 1 loss to the Broncos.

Key players to watch:

Indianapolis Colts

- QB Daniel Jones - Jones has been impressive in Indy’s 2-0 start, completing 71.4% of passes for 588 yards with no interceptions and a league-high 9.3 yards per attempt. His quick processing and play-action usage have boosted the Colts’ second-ranked offense against Tennessee’s weak pass rush. Jones is expected to exploit underneath routes and extend plays, potentially surpassing 250 yards. His turnover-free streak makes him a reliable choice to maintain momentum in this divisional game.

- RB Jonathan Taylor - Taylor leads the NFL with 236 rushing yards in two games, including a 165 yard performance against the Broncos’ stout run defense. He continues regained his form under Shane Steichen’s RPO-heavy scheme. Despite missing key interior lineman T’Vondre Sweat to injury, the Titans rank 29th against the run. Taylor’s explosive running ability could lead to a 100+ yard rushing game and a touchdown. The last time these two teams met, Taylor rushed for an impressive 218 yards and scored three touchdowns.

- WR Alec Pierce - As a deep threat, Pierce thrives in Indianapolis’ vertical attack. His 20+ yards per play, which showcases his potential for big plays. With QB Daniel Jones’ accuracy on long passes and Tennessee’s secondary vulnerable after allowing significant plays to the Rams, Pierce can stretch the field for big gains. This makes him a high-upside fantasy addition if you’re looking for explosive plays.

Tennessee Titans

- QB Cam Ward - The first-overall pick has shown poise in avoiding turnovers but has taken 11 sacks behind the league's worst offensive line (last in yards and pass completions at 50.8%). This is his first start against a below-average pass rush, giving Ward a chance to air it out with his arm strength. If Brian Callahan dials up simple concepts, Ward could hit 200+ yards and a score, but Indy's veteran secondary (led by Kenny Moore and Charvarius Ward) will test his pocket presence. Watch for quick decisions or scrambles to spark Tennessee's stagnant offense.

- WR Calvin Ridley - Ridley's speed makes him Ward's top target, but he'll face a tough matchup in Indy's physical corners. With the Titans desperate for explosive plays (just one TD in two games), Ridley's route-running could draw targets on slants and fades, especially if Ward gets time. He's a volume play in a must win spot for Tennessee, potentially rebounding for a big game if the rookie settles in.

- DT Jeffrey Simmons - Simmons has been a one-man wrecking crew with 10 pressures, 5 hits, and 4 hurries in two games, anchoring Dennard Wilson's aggressive front. Without Sweat, he'll slide inside more. Simmons could disrupt with 1-2 sacks on the Colts offensive line. His pass rush upside keeps Tennessee competitive, forcing turnovers (5) to stay in the fourth quarter.

These two teams are always locked in a fierce battle, but my prediction is that the Colts will emerge victorious with a score of 28-17.